Title : An eIF5/eIF2 complex antagonizes guanine nucleotide exchange by eIF2B during translation initiation.

Pub. Date : 2006 Oct 4

PMID : 16990799






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 In eukaryotic translation initiation, the eIF2.GTP/Met-tRNA(i)(Met) ternary complex (TC) binds the eIF3/eIF1/eIF5 complex to form the multifactor complex (MFC), whereas eIF2.GDP binds the pentameric factor eIF2B for guanine nucleotide exchange. Guanosine Diphosphate eukaryotic translation initiation factor 5 Homo sapiens