Pub. Date : 2006 Sep 27
PMID : 16984172
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This new approach resulted in potent, reversible, competitive inhibitors of caspase-1 (IC50 < 10 nM), with significant advantages over aldehydes such as high stability in vitro to thiols (10 mM dithiothreitol (pH 7.2), 20 mM glutathione (pH 7.2, 9, 11)) and aqueous media, as well as some highly desirable druglike features. | Sulfhydryl Compounds | caspase 1 | Homo sapiens |