Title : The effects of different immunosuppressants on chronic allograft nephropathy by affecting the transforming growth factor-beta and Smads signal pathways.

Pub. Date : 2006 Sep

PMID : 16980029






1 Functional Relationships(s)
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1 RESULTS: CsA and FK506 stimulated gene expression and protein production of TGF-beta1, smad2, and smad3, but inhibited expression of smad7 both in VSMC and in the transplanted kidney. Tacrolimus transforming growth factor, beta 1 Rattus norvegicus