Pub. Date : 2006 Nov
PMID : 16978829
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Using enzyme-linked immunosorbent assays (ELISAs) we showed DHMEQ to inhibit LPS-induced secretion of IL-6, IL-12, interleukin-1beta (IL-1beta), and TNF-alpha. | dehydroxymethylepoxyquinomicin | interleukin 1 beta | Mus musculus |
2 | Using enzyme-linked immunosorbent assays (ELISAs) we showed DHMEQ to inhibit LPS-induced secretion of IL-6, IL-12, interleukin-1beta (IL-1beta), and TNF-alpha. | dehydroxymethylepoxyquinomicin | interleukin 1 beta | Mus musculus |
3 | Furthermore, DHMEQ also inhibited the phagocytosis of fluorescently labeled Escherichia coli by RAW264.7 cells treated with LPS or IL-1beta, thus being the first evidence for the involvement of NF-kappaB in the regulation of phagocytosis by use of this inhibitor. | dehydroxymethylepoxyquinomicin | interleukin 1 beta | Mus musculus |