Title : Simultaneous activation of viral antigen-specific memory CD4+ and CD8+ T-cells using mRNA-electroporated CD40-activated autologous B-cells.

Pub. Date : 2006 Sep-Oct

PMID : 16971807






1 Functional Relationships(s)
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1 These cells not only express and secrete the HIV p24 antigen after electroporation with codon-optimized HIV-1 gag mRNA, but can also be used to in vitro reactivate Gag antigen-specific interferon-gamma-producing CD4 and CD8 autologous T-cells. Glycosaminoglycans CD4 molecule Homo sapiens