Title : Thrombospondin-1 C-terminal-derived peptide protects thyroid cells from ceramide-induced apoptosis through the adenylyl cyclase pathway.

Pub. Date : 2006

PMID : 16971166






3 Functional Relationships(s)
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Protein Name
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1 Thrombospondin-1 C-terminal-derived peptide protects thyroid cells from ceramide-induced apoptosis through the adenylyl cyclase pathway. Ceramides thrombospondin 1 Homo sapiens
2 In this work, we examined the role of thrombospondin-1 in ceramide-induced thyroid apoptosis. Ceramides thrombospondin 1 Homo sapiens
3 Furthermore, we demonstrated that the thrombospondin-1-derived peptide 4N1 (RFYVVMWK) abolished ceramide-induced thyroid cell death by preventing intracellular cAMP levels from dropping. Ceramides thrombospondin 1 Homo sapiens