Title : The thiazolidinedione drug troglitazone up-regulates nitric oxide synthase expression in vascular endothelial cells.

Pub. Date : 2006 Sep-Oct

PMID : 16949522






2 Functional Relationships(s)
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1 Troglitazone up-regulated eNOS protein and its mRNA levels, whereas pioglitazone and 15-dPGJ2 failed to increase their levels. Troglitazone nitric oxide synthase 3 Homo sapiens
2 These results suggest that troglitazone up-regulates eNOS expression probably through its 6-hydroxychromanes structure but not activating PPARgamma. Troglitazone nitric oxide synthase 3 Homo sapiens