Pub. Date : 2006 Dec
PMID : 16933034
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Angiotensin II modulates tyr-phosphorylation of IRS-4, an insulin receptor substrate, in rat liver membranes. | Tyrosine | angiotensinogen | Rattus norvegicus |
| 2 | Pre-stimulation with Ang II (10(-7) M) diminishes tyr-phosphorylation level of pp160/IRS-4 in a dose-dependent manner. | Tyrosine | angiotensinogen | Rattus norvegicus |
| 3 | These results suggest that Ins and Ang II modulate IRS-4 tyr-phosphorylation in a PI3K-dependent manner. | Tyrosine | angiotensinogen | Rattus norvegicus |
| 4 | In summary, we showed that Ins induces tyr-phosphorylation of IRS-4, an effect modulated by Ang II. | Tyrosine | angiotensinogen | Rattus norvegicus |