Pub. Date : 2006 Aug
PMID : 16928825
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effects of bortezomib were associated with accumulation of p21 and mimicked by chemical CDK inhibitors or by transfecting cells with a small interfering RNA construct specific for CDK1. | Bortezomib | cyclin dependent kinase 1 | Homo sapiens |
| 2 | Together, our data show that bortezomib interferes with docetaxel-induced apoptosis via a p21-dependent mechanism that is associated with CDK1 inhibition. | Bortezomib | cyclin dependent kinase 1 | Homo sapiens |