Title : [Dihydropyrimidine dehydrogenase activity and its genetic aberrations].

Pub. Date : 2006 Aug

PMID : 16912518






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Dihydropyrimidine dehydrogenase (DPD, EC 1.3.1.2) is the initial and rate-limiting enzyme in the catabolism of the pyrimidine bases, uracil and thymine, and is also known to be the key enzyme catalyzing the metabolic degradation of the anti-cancer drug 5-fluorouracil (5-FU). Uracil dihydropyrimidine dehydrogenase Homo sapiens
2 Dihydropyrimidine dehydrogenase (DPD, EC 1.3.1.2) is the initial and rate-limiting enzyme in the catabolism of the pyrimidine bases, uracil and thymine, and is also known to be the key enzyme catalyzing the metabolic degradation of the anti-cancer drug 5-fluorouracil (5-FU). Uracil dihydropyrimidine dehydrogenase Homo sapiens