Title : XRCC1 R399Q polymorphism is associated with response to platinum-based neoadjuvant chemotherapy in bulky cervical cancer.

Pub. Date : 2006 Dec

PMID : 16875718






3 Functional Relationships(s)
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1 RESULTS: The response to platinum-based NAC was higher in patients with SNP of XRCC1 R399Q (P=0.015), and there was a significant increased chance of treatment response in women with the G/G genotype (OR 38.0; 95% CI 1.66-870.45; P=0.023). nac X-ray repair cross complementing 1 Homo sapiens
2 CONCLUSIONS: Genetic polymorphism of XRCC1 R399Q is associated with response to platinum-based NAC in bulky cervical cancer, and MDR analysis documented association between gene-gene interaction of XRCC1 R399Q and treatment response. nac X-ray repair cross complementing 1 Homo sapiens
3 CONCLUSIONS: Genetic polymorphism of XRCC1 R399Q is associated with response to platinum-based NAC in bulky cervical cancer, and MDR analysis documented association between gene-gene interaction of XRCC1 R399Q and treatment response. nac X-ray repair cross complementing 1 Homo sapiens