Title : Inhibitory effects of cytostatically active 6-aminobenzo[c]phenanthridines on cytochrome P450 enzymes in human hepatic microsomes.

Pub. Date : 2006 Jul

PMID : 16867169






1 Functional Relationships(s)
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1 In detail these selective substrates were caffeine (CYP1A2), coumarin (CYP2A6), tolbutamide (CYP2C9), S-(+)-mephenytoin (CYP2C19), dextromethorphane (CYP2D6), chlorzoxazone (CYP2E1) and testosterone (CYP3A4). Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens