Title : Protective effects of minocycline on 3,4-methylenedioxymethamphetamine-induced neurotoxicity in serotonergic and dopaminergic neurons of mouse brain.

Pub. Date : 2006 Aug 21

PMID : 16859675






3 Functional Relationships(s)
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1 The repeated administration of MDMA (10 mg/kg x 3, 3-h intervals, s.c.) significantly decreased the contents of the dopamine and the density of the dopamine transporter (DAT) in the striatum, but not the frontal cortex. N-Methyl-3,4-methylenedioxyamphetamine solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus
2 The repeated administration of MDMA (10 mg/kg x 3, 3-h intervals, s.c.) significantly decreased the contents of the dopamine and the density of the dopamine transporter (DAT) in the striatum, but not the frontal cortex. N-Methyl-3,4-methylenedioxyamphetamine solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus
3 significantly attenuated the reduction of 5-HT and dopamine as well as the density of 5-HTT and DAT in the mouse brain by the repeated administration of MDMA. N-Methyl-3,4-methylenedioxyamphetamine solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 Mus musculus