Title : Stimulatory effect of glutamine on human monocyte activation as measured by interleukin-6 and soluble interleukin-6 receptor release.

Pub. Date : 1997 Jun

PMID : 16844584






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1 Stimulatory effect of glutamine on human monocyte activation as measured by interleukin-6 and soluble interleukin-6 receptor release. Glutamine interleukin 6 Homo sapiens
2 Stimulatory effect of glutamine on human monocyte activation as measured by interleukin-6 and soluble interleukin-6 receptor release. Glutamine interleukin 6 Homo sapiens
3 The extracellular glutamine concentration had a significant effect on IL-6 secretion by activated human monocytes. Glutamine interleukin 6 Homo sapiens
4 The mean levels of IL-6 in 0.1 mM glutamine were only marginally higher (P = 0.54) compared to those in the absence of glutamine. Glutamine interleukin 6 Homo sapiens
5 A minimum of 0.2 mM glutamine was required to reach the maximal production of IL-6. Glutamine interleukin 6 Homo sapiens
6 At all glutamine concentrations the higher concentration of LPS (1 ng/ml) induced higher mean levels of IL-6 than the lower one (1 pg/ml). Glutamine interleukin 6 Homo sapiens
7 Our results indicate that very low levels of glutamine in plasma may impair the activation of human monocytes as measured by IL-6 secretion. Glutamine interleukin 6 Homo sapiens