Pub. Date : 2006 Oct
PMID : 16837624
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By investigating how MNS inhibits GPIIb/IIIa activation, we found that MNS potently inhibited the activity of tyrosine kinases (Src and Syk) and prevented protein tyrosine phosphorylation and cytoskeletal association of GPIIb/IIIa and talin, but it had no direct effects on protein kinase C, Ca2+ mobilization, Ca2+-dependent enzymes (myosin light chain kinase and calpain), and arachidonic acid metabolism, and it did not affect the cellular levels of cyclic nucleotides. | Tyrosine | integrin subunit alpha 2b | Homo sapiens |