Pub. Date : 2006 Sep
PMID : 16832657
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Differential role of 5-HT1A and 5-HT1B receptors on the antinociceptive and antidepressant effect of tramadol in mice. | Tramadol | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
| 2 | OBJECTIVES: The present study was undertaken to evaluate the potential role of 5-HT1A and 5-HT1B receptors on the analgesic and antidepressant-like effect of tramadol. | Tramadol | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
| 3 | CONCLUSIONS: These findings suggest that 5-HT1A receptors modulate the analgesic and the antidepressant-like effects of tramadol in differing ways. | Tramadol | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
| 4 | In contrast, the 5-HT1A receptors located in the forebrain may be responsible for the blockade of the antidepressant-like effect of tramadol. | Tramadol | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |