Protein Name 5-hydroxytryptamine (serotonin) receptor 1A
Organism Mus musculus
Gene ID 15550
Gene Symbol


UniProt Q64264 (5HT1A_MOUSE)
Relationships Total Number of functionally related compound(s) : 517
Total Number of Articles : 800

5-hydroxytryptamine (serotonin) receptor 1A

Gene Summary

Enables G protein-coupled serotonin receptor activity. Involved in several processes, including behavioral fear response; serotonin metabolic process; and serotonin receptor signaling pathway. Acts upstream of or within gamma-aminobutyric acid signaling pathway. Predicted to be located in axon hillock. Predicted to be active in dendrite. Predicted to be integral component of plasma membrane. Is expressed in several structures, including central nervous system; exocrine gland; eye; genitourinary system; and intestine. Used to study anxiety disorder. Human ortholog(s) of this gene implicated in anxiety disorder; mental depression; and panic disorder. Orthologous to human HTR1A (5-hydroxytryptamine receptor 1A). [provided by Alliance of Genome Resources, Apr 2022]

  • 5-hydroxytryptamine receptor 1A
  • 5-HT-1A
  • 5-HT1A receptor
Click to show/hide the synonyms