Pub. Date : 2006 Sep
PMID : 16797759
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | By Western blot, the expression of 14-3-3sigma, p53 and p21 was coordinately upregulated in astrocytes following exposure to hydrogen peroxide, 4-hydroxy-2-nonenal (4-HNE) or etoposide, a topoisomerase II inhibitor. | 4-hydroxy-2-nonenal | stratifin | Homo sapiens |
| 2 | By Western blot, the expression of 14-3-3sigma, p53 and p21 was coordinately upregulated in astrocytes following exposure to hydrogen peroxide, 4-hydroxy-2-nonenal (4-HNE) or etoposide, a topoisomerase II inhibitor. | 4-hydroxy-2-nonenal | stratifin | Homo sapiens |
| 3 | In vivo, a small subset of hypertrophic reactive astrocytes, often showing a multinucleated morphology, expressed 14-3-3sigma in active demyelinating lesions of multiple sclerosis (MS) and ischemic lesions of cerebral infarction, where the expression of 4-HNE and 8-hydroxy-2"-deoxyguanosine was enhanced in reactive astrocytes. | 4-hydroxy-2-nonenal | stratifin | Homo sapiens |