Title : Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo.

Pub. Date : 2006 Jul

PMID : 16783563






2 Functional Relationships(s)
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1 Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo. Debrisoquin cytochrome P450 family 2 subfamily C member 9 Homo sapiens
2 The CYP2D6 and CYP2C9 activities of the subjects were measured by debrisoquine and losartan phenotyping tests, respectively. Debrisoquin cytochrome P450 family 2 subfamily C member 9 Homo sapiens