Title : Procaterol upregulates peroxisome proliferator-activated receptor-gamma expression in human eosinophils.

Pub. Date : 2006

PMID : 16772725






2 Functional Relationships(s)
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1 In this study, we investigated the effect of procaterol, the synthetic beta2-adrenoceptor agonist widely used as bronchodilators in asthma, on the PPARgamma expression in eosinophils. Procaterol adrenoceptor beta 2 Homo sapiens
2 We observed that PPARgamma was constitutively expressed by EoL-1 and the purified eosinophils and that the therapeutic concentration (10(-9)M) of procaterol markedly enhanced PPARgamma protein expression, which was reversed by the selective beta2-adrenoceptor antagonist ICI-118551. Procaterol adrenoceptor beta 2 Homo sapiens