Title : Modulation of signal transducer and activator of transcription 5b activity in breast cancer cells by mutation of tyrosines within the transactivation domain.

Pub. Date : 2006 Oct

PMID : 16772534






2 Functional Relationships(s)
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1 Modulation of signal transducer and activator of transcription 5b activity in breast cancer cells by mutation of tyrosines within the transactivation domain. Tyrosine signal transducer and activator of transcription 5B Homo sapiens
2 Although phosphorylation of STAT5b on Y699 is required for activation, it was previously shown that in epidermal growth factor receptor (EGFR)-overexpressing cell lines, three tyrosines (Y725, Y740, and Y743) in the STAT5b transactivation domain are also phosphorylated upon epidermal growth factor stimulation. Tyrosine signal transducer and activator of transcription 5B Homo sapiens