Pub. Date : 2006 Jul
PMID : 16767098
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | When given orally to a transgenic mouse model of Alzheimer disease, cyclohexanehexol stereoisomers inhibit aggregation of amyloid beta peptide (Abeta) into high-molecular-weight oligomers in the brain and ameliorate several Alzheimer disease-like phenotypes in these mice, including impaired cognition, altered synaptic physiology, cerebral Abeta pathology and accelerated mortality. | Inositol | amyloid beta (A4) precursor protein | Mus musculus |
| 2 | When given orally to a transgenic mouse model of Alzheimer disease, cyclohexanehexol stereoisomers inhibit aggregation of amyloid beta peptide (Abeta) into high-molecular-weight oligomers in the brain and ameliorate several Alzheimer disease-like phenotypes in these mice, including impaired cognition, altered synaptic physiology, cerebral Abeta pathology and accelerated mortality. | Inositol | amyloid beta (A4) precursor protein | Mus musculus |