Pub. Date : 2006 Jul
PMID : 16764943
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Recently, we demonstrated that administration of the PPAR-alpha agonists gemfibrozil and fenofibrate, inhibit the clinical signs of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). | Gemfibrozil | peroxisome proliferator activated receptor alpha | Mus musculus |
2 | Interestingly, a combination of 9-cis RA and the PPAR-alpha agonists fenofibrate or gemfibrozil cooperatively inhibited NO, TNF-alpha, IL-1beta, IL-6, and MCP-1 production by these cells. | Gemfibrozil | peroxisome proliferator activated receptor alpha | Mus musculus |