Pub. Date : 1991 Jul
PMID : 1675220
10 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Mitotane enhances cytotoxicity of chemotherapy in cell lines expressing a multidrug resistance gene (mdr-1/P-glycoprotein) which is also expressed by adrenocortical carcinomas. | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | Mitotane enhances cytotoxicity of chemotherapy in cell lines expressing a multidrug resistance gene (mdr-1/P-glycoprotein) which is also expressed by adrenocortical carcinomas. | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | The present study demonstrates that decreased drug accumulation mediated by mdr-1/Pgp can be overcome by clinically achievable concentrations of mitotane (o,p"-DDD). | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | The present study demonstrates that decreased drug accumulation mediated by mdr-1/Pgp can be overcome by clinically achievable concentrations of mitotane (o,p"-DDD). | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | The present study demonstrates that decreased drug accumulation mediated by mdr-1/Pgp can be overcome by clinically achievable concentrations of mitotane (o,p"-DDD). | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 6 | The present study demonstrates that decreased drug accumulation mediated by mdr-1/Pgp can be overcome by clinically achievable concentrations of mitotane (o,p"-DDD). | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 7 | The finding that multidrug resistance mediated by mdr-1/Pgp can be reversed by mitotane provides a rational basis for exploring the use of mitotane in combination with natural product chemotherapeutic agents in adrenocortical cancer. | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 8 | The finding that multidrug resistance mediated by mdr-1/Pgp can be reversed by mitotane provides a rational basis for exploring the use of mitotane in combination with natural product chemotherapeutic agents in adrenocortical cancer. | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 9 | The finding that multidrug resistance mediated by mdr-1/Pgp can be reversed by mitotane provides a rational basis for exploring the use of mitotane in combination with natural product chemotherapeutic agents in adrenocortical cancer. | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 10 | The finding that multidrug resistance mediated by mdr-1/Pgp can be reversed by mitotane provides a rational basis for exploring the use of mitotane in combination with natural product chemotherapeutic agents in adrenocortical cancer. | Mitotane | ATP binding cassette subfamily B member 1 | Homo sapiens |