Title : Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage.

Pub. Date : 2006 Jun 13

PMID : 16751265






1 Functional Relationships(s)
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Protein Name
Organism
1 Cells lacking Tdp1 are hypersensitive to camptothecin, consistent with a role for Tdp1 in processing 3" phosphotyrosyl protein-DNA covalent complexes. Camptothecin tyrosyl-DNA phosphodiesterase 1 Saccharomyces cerevisiae S288C