Title : Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase.

Pub. Date : 2006 Jul 21

PMID : 16728407






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The TSC1-2 tumor suppressor complex has been shown to act as a RhebGAP, converting Rheb from a GTP-bound to a GDP-bound form. Guanosine Diphosphate Ras homolog, mTORC1 binding Homo sapiens