Title : Estrogen-mediated regulation of CYP7B1: a possible role for controlling DHEA levels in human tissues.

Pub. Date : 2006 Jul

PMID : 16720094






4 Functional Relationships(s)
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1 Estrogen-mediated regulation of CYP7B1: a possible role for controlling DHEA levels in human tissues. Dehydroepiandrosterone cytochrome P450 family 7 subfamily B member 1 Homo sapiens
2 Since CYP7B1 diverts DHEA from the sex hormone biosynthetic pathway, estrogen receptor-mediated up-regulation of CYP7B1 should lead to less DHEA available for sex hormone synthesis and may help to maintain normal levels of estrogens and androgens in human tissues, especially during fetal development. Dehydroepiandrosterone cytochrome P450 family 7 subfamily B member 1 Homo sapiens
3 Since CYP7B1 diverts DHEA from the sex hormone biosynthetic pathway, estrogen receptor-mediated up-regulation of CYP7B1 should lead to less DHEA available for sex hormone synthesis and may help to maintain normal levels of estrogens and androgens in human tissues, especially during fetal development. Dehydroepiandrosterone cytochrome P450 family 7 subfamily B member 1 Homo sapiens
4 Since CYP7B1 diverts DHEA from the sex hormone biosynthetic pathway, estrogen receptor-mediated up-regulation of CYP7B1 should lead to less DHEA available for sex hormone synthesis and may help to maintain normal levels of estrogens and androgens in human tissues, especially during fetal development. Dehydroepiandrosterone cytochrome P450 family 7 subfamily B member 1 Homo sapiens