Title : Functional reconstitution of Beta2-adrenergic receptors utilizing self-assembling Nanodisc technology.

Pub. Date : 2006 May

PMID : 16708760






4 Functional Relationships(s)
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1 Here we report a technique for self-assembling functional beta2-adrenergic receptor (beta2AR) into a nanoscale phospholipid bilayer system (Nanodisc) that is highly soluble in aqueous solution. Phospholipids adrenoceptor beta 2 Homo sapiens
2 Here we report a technique for self-assembling functional beta2-adrenergic receptor (beta2AR) into a nanoscale phospholipid bilayer system (Nanodisc) that is highly soluble in aqueous solution. Phospholipids adrenoceptor beta 2 Homo sapiens
3 The approximately 10-nm nanobilayer particles contain beta2AR in a native-like phospholipid bilayer domain of approximately 100 phospholipid molecules circumferentially bound by a membrane scaffold protein (MSP). Phospholipids adrenoceptor beta 2 Homo sapiens
4 The approximately 10-nm nanobilayer particles contain beta2AR in a native-like phospholipid bilayer domain of approximately 100 phospholipid molecules circumferentially bound by a membrane scaffold protein (MSP). Phospholipids adrenoceptor beta 2 Homo sapiens