Pub. Date : 2006 Jul 21
PMID : 16702225
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | These studies reveal that binding of a pY peptide to the N-SH2 domain of SHP-2 is greatly enhanced by a large hydrophobic residue (Trp, Tyr, Met, or Phe) at the pY+4 and/or pY+5 positions, whereas binding to SHP-1 N-SH2 domain is enhanced by either hydrophobic or positively charged residues (Arg, Lys, or His) at these positions. | Phenylalanine | protein tyrosine phosphatase non-receptor type 11 | Homo sapiens |