Title : Amitriptyline suppresses neuroinflammation and up-regulates glutamate transporters in morphine-tolerant rats.

Pub. Date : 2006 Sep

PMID : 16697108






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Glial cells activation and increased cytokine expression (TNFalpha, IL-1beta, and IL-6) in the rat spinal cord were induced by the 5-day morphine infusion and these neuroimmune responses were also prevented by amitriptyline co-infusion. Morphine tumor necrosis factor Rattus norvegicus