Pub. Date : 2006 May
PMID : 16689752
9 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Upon heparin infusion during cardiopulmonary bypass (CPB), a heparin releasable pool of endothelial associated TFPI circulates in plasma. | Heparin | tissue factor pathway inhibitor | Homo sapiens |
| 2 | Upon heparin infusion during cardiopulmonary bypass (CPB), a heparin releasable pool of endothelial associated TFPI circulates in plasma. | Heparin | tissue factor pathway inhibitor | Homo sapiens |
| 3 | Following protamine neutralization of heparin, the plasma TFPI level decreases, but does not return completely to baseline, suggesting that during CPB a fraction of the plasma TFPI becomes heparin-independent. | Heparin | tissue factor pathway inhibitor | Homo sapiens |
| 4 | Following protamine neutralization of heparin, the plasma TFPI level decreases, but does not return completely to baseline, suggesting that during CPB a fraction of the plasma TFPI becomes heparin-independent. | Heparin | tissue factor pathway inhibitor | Homo sapiens |
| 5 | RESULTS: The ELISA and Western blot data indicated that an increase in full-length TFPI accounted for most of the heparin releasable TFPI. | Heparin | tissue factor pathway inhibitor | Homo sapiens |
| 6 | RESULTS: The ELISA and Western blot data indicated that an increase in full-length TFPI accounted for most of the heparin releasable TFPI. | Heparin | tissue factor pathway inhibitor | Homo sapiens |
| 7 | Following heparin neutralization with protamine, the full-length TFPI antigen returned to baseline levels while the free TFPI antigen and the total plasma TFPI activity remained elevated. | Heparin | tissue factor pathway inhibitor | Homo sapiens |
| 8 | CONCLUSIONS: During CPB the full-length form of TFPI is the predominant form in plasma because of its prompt release from the endothelial surface following heparin administration. | Heparin | tissue factor pathway inhibitor | Homo sapiens |
| 9 | Upon heparin neutralization with protamine, full-length TFPI redistributes back to the endothelial surface. | Heparin | tissue factor pathway inhibitor | Homo sapiens |