Title : Combination treatment with arsenic trioxide and sulindac augments their apoptotic potential in lung cancer cells through activation of caspase cascade and mitochondrial dysfunction.

Pub. Date : 2006 Jun

PMID : 16685442






1 Functional Relationships(s)
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1 In addition, combination treatment with As2O3 and sulindac increased the catalytic activity of caspase-3, -8, and -9 along with induction of Fas/FasL expression and cytosolic release of cytochrome c. Arsenic Trioxide Fas ligand Homo sapiens