Title : Montelukast and zafirlukast do not affect the pharmacokinetics of the CYP2C8 substrate pioglitazone.

Pub. Date : 2006 Jul

PMID : 16670899






1 Functional Relationships(s)
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1 OBJECTIVE: Pioglitazone, a thiazolidinedione antidiabetic drug, is metabolised mainly by the cytochrome P450 (CYP) 2C8 enzyme. 2,4-thiazolidinedione cytochrome P450 family 2 subfamily C member 8 Homo sapiens