Pub. Date : 1991 Sep
PMID : 1664996
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Hydrogen peroxide-dependent oxidation metabolism of 1-methyl-2-mercaptoimidazole (methimazole) catalysed by myeloperoxidase. | Methimazole | myeloperoxidase | Homo sapiens |
| 2 | Hydrogen peroxide-dependent oxidation metabolism of 1-methyl-2-mercaptoimidazole (methimazole) catalysed by myeloperoxidase. | Methimazole | myeloperoxidase | Homo sapiens |
| 3 | Myeloperoxidase catalysed the H2O2-supported oxidation of 1-methyl-2-mercaptoimidazole (MMI) in the presence of Cl-. | Methimazole | myeloperoxidase | Homo sapiens |
| 4 | Myeloperoxidase catalysed the H2O2-supported oxidation of 1-methyl-2-mercaptoimidazole (MMI) in the presence of Cl-. | Methimazole | myeloperoxidase | Homo sapiens |
| 5 | When the H2O2/MMI ratio was 0.5, MMI was oxidized by hyochlorous acid produced by the myeloperoxidase-H2O2-Cl- system giving bis-(1-methyl-2-imidazolyl)disulphide (MMI-disulphide) as an initial product, which gradually underwent disproportionation and subsequent hydrolysis giving 1-methylimidazole and MMI as the final products stoichiometrically. | Methimazole | myeloperoxidase | Homo sapiens |