Title : c-Abl acetylation by histone acetyltransferases regulates its nuclear-cytoplasmic localization.

Pub. Date : 2006 Jul

PMID : 16648821






2 Functional Relationships(s)
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1 Indeed, acetylation on Lys 730 drives c-Abl accumulation in the cytoplasm and promotes differentiation. Lysine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 Thus, Lys 730 acetylation is a novel post-translational modification of c-Abl and a novel mechanism for modulating its subcellular localization that contributes to myogenic differentiation. Lysine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens