Title : Cilostazol protects against brain white matter damage and cognitive impairment in a rat model of chronic cerebral hypoperfusion.

Pub. Date : 2006 Jun

PMID : 16645134






1 Functional Relationships(s)
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1 CONCLUSIONS: Our results indicate that cilostazol exerts a brain-protective effect through the CREB phosphorylation pathway leading to upregulation of Bcl-2 and COX-2 expressions and suggest that cilostazol is potentially useful for the treatment of cognitive impairment in poststroke patients. Cilostazol cAMP responsive element binding protein 1 Homo sapiens