Title : Functional proteomics identifies protein-tyrosine phosphatase 1B as a target of RhoA signaling.

Pub. Date : 2006 Aug

PMID : 16644720






1 Functional Relationships(s)
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1 Subsequent analysis demonstrated that RhoA enhances post-translational modification of PTP1B, inactivates phosphotyrosine phosphatase activity, and up-regulates tyrosine phosphorylation of p130Cas, a key mediator of focal adhesion turnover and cell migration. Tyrosine ras homolog family member A Homo sapiens