Title : Cellular accumulation and activity of quinolones in ciprofloxacin-resistant J774 macrophages.

Pub. Date : 2006 May

PMID : 16641436






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Compared to wild-type cells, ciprofloxacin-resistant cells showed (i) a markedly reduced ciprofloxacin accumulation (12% of control) and (ii) a two- to threefold lower sensitivity to the enhancing effect exerted by MRP-inhibitors (probenecid and MK571) on ciprofloxacin accumulation or by ciprofloxacin itself. verlukast ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mus musculus