Title : Effects of resveratrol on mast cell degranulation and tyrosine phosphorylation of the signaling components of the IgE receptor.

Pub. Date : 2006 Jun

PMID : 16636972






2 Functional Relationships(s)
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1 Resveratrol inhibited mast cell degranulation in a dose-dependent manner and reduced the FcepsilonRI-mediated tyrosine phosphorylation of ERK and PLCgamma1 but not of Syk and PLCgamma2. Tyrosine phospholipase C gamma 1 Homo sapiens
2 These results suggest that FcepsilonRI-mediated tyrosine phosphorylation of PLCgamma1 and ERK could be potential cellular targets of resveratrol for the inhibition of mast cell degranulation. Tyrosine phospholipase C gamma 1 Homo sapiens