Title : ADAM10 activation is required for green tea (-)-epigallocatechin-3-gallate-induced alpha-secretase cleavage of amyloid precursor protein.

Pub. Date : 2006 Jun 16

PMID : 16624814






1 Functional Relationships(s)
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1 Recently, we have shown that green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) exerts a beneficial role on reducing brain Abeta levels, resulting in mitigation of cerebral amyloidosis in a mouse model of Alzheimer disease. Polyphenols amyloid beta (A4) precursor protein Mus musculus