Title : Piperine inhibition of 1-methyl-4-phenylpyridinium-induced mitochondrial dysfunction and cell death in PC12 cells.

Pub. Date : 2006 May 10

PMID : 16624279






1 Functional Relationships(s)
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1 Piperine at low concentrations may reduce the MPP(+)-induced viability loss in PC12 cells by suppressing the changes in the mitochondrial membrane permeability, leading to the release of cytochrome c and subsequent activation of caspase-3. piperine caspase 3 Rattus norvegicus