Pub. Date : 2006 Jun
PMID : 16616699
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We observed that EPA or DHA alone significantly reduced the TNF-alpha-induced activation of p38 and JNK kinases at a concentration of 20 microM, but EPA is a more potent inhibitor than DHA. | Docosahexaenoic Acids | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | Meanwhile, both EPA and DHA significantly attenuated the TNF-alpha-induced expression of p38 and ERK1/2 mRNA, and DHA but not EPA also reduced the TNF-alpha-induced JNK mRNA expression. | Docosahexaenoic Acids | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | We present data show that both EPA and DHA alone diminish activation of p38 and JNK kinases, while maintaining the activation of ERK1/2 kinases of TNF-alpha-stimulated HUVEC. | Docosahexaenoic Acids | mitogen-activated protein kinase 1 | Homo sapiens |