Title : Recovery of hepatic function determined by cytochrome P450-dependent drug metabolism lags after compensatory hepatic volume changes after portal vein ligation in rats.

Pub. Date : 2006 Aug

PMID : 16564546






1 Functional Relationships(s)
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1 To evaluate in vivo the effect of PVL on hepatic drug metabolism, the narcotic activity (sleep time) of midazolam, a specific substrate for CYP3A2, was measured. Midazolam cytochrome P450, family 3, subfamily a, polypeptide 2 Rattus norvegicus