Title : Differential upregulation of Nox homologues of NADPH oxidase by tumor necrosis factor-alpha in human aortic smooth muscle and embryonic kidney cells.

Pub. Date : 2006 Jan-Mar

PMID : 16563235






3 Functional Relationships(s)
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1 Previously we demonstrated that the Nox4 subunit of NADPH oxidase is a critical catalytic component for superoxide production in quiescent vascular smooth muscle cells. Superoxides NADPH oxidase 4 Homo sapiens
2 In this study we sought to determine the role of Nox4 in superoxide production in human aortic smooth muscle cells (AoSMC) and embryonic kidney (HEK293) cells under proinflammatory conditions. Superoxides NADPH oxidase 4 Homo sapiens
3 We suggest that Nox4 may be involved in increased superoxide generation in vascular smooth muscle cells under proinflammatory conditions. Superoxides NADPH oxidase 4 Homo sapiens