Title : Mutations in the juxtamembrane region of the insulin receptor impair activation of phosphatidylinositol 3-kinase by insulin.

Pub. Date : 1991 Jun

PMID : 1656240






1 Functional Relationships(s)
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1 CHO/IRF960/T962 cells express a mutant human insulin receptor in which Tyr960 and Ser962 in the juxtamembrane region of the receptor"s beta-subunit are replaced by Phe and Thr, respectively. Phenylalanine insulin receptor Homo sapiens