Pub. Date : 1991 Nov
PMID : 1655978
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In previous studies we found that NGF production is up-regulated by 12-O-tetradecanoylphorbol 13-acetate (TPA) and serum, down-regulated by corticosterone, and unaffected by dibutyryl-cyclic AMP (db-cyclic AMP) in fibroblasts. | Tetradecanoylphorbol Acetate | nerve growth factor | Homo sapiens |
| 2 | In previous studies we found that NGF production is up-regulated by 12-O-tetradecanoylphorbol 13-acetate (TPA) and serum, down-regulated by corticosterone, and unaffected by dibutyryl-cyclic AMP (db-cyclic AMP) in fibroblasts. | Tetradecanoylphorbol Acetate | nerve growth factor | Homo sapiens |
| 3 | TPA and serum together stimulated NGF production 10-fold more than either agent alone. | Tetradecanoylphorbol Acetate | nerve growth factor | Homo sapiens |
| 4 | Forskolin and db-cyclic AMP prevented NGF mRNA induction by TPA and serum without changing basal levels. | Tetradecanoylphorbol Acetate | nerve growth factor | Homo sapiens |
| 5 | TPA induced c-fos and junB mRNAs transiently and preceding NGF mRNA induction but c-jun mRNA remained undetectable. | Tetradecanoylphorbol Acetate | nerve growth factor | Homo sapiens |
| 6 | Thus, TPA induction of NGF mRNA is modulated differentially by corticosterone and cyclic AMP. | Tetradecanoylphorbol Acetate | nerve growth factor | Homo sapiens |