Title : CysLT1 receptor-induced human airway smooth muscle cells proliferation requires ROS generation, EGF receptor transactivation and ERK1/2 phosphorylation.

Pub. Date : 2006 Mar 22

PMID : 16553950






1 Functional Relationships(s)
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1 CONCLUSION: Collectively, our data demonstrate that in HASMC LTD4 stimulation of a Gi/o coupled CysLT1-R triggers the transactivation of the EGF-R through the intervention of PI3K and ROS. Reactive Oxygen Species epidermal growth factor receptor Homo sapiens