Pub. Date : 2006 Jul
PMID : 16533604
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ET-743, a DNA minor groove binder, which blocks cell cycle progression in G2/M phase through a p53-independent apoptotic process, represents the most promising among novel compounds in STS, since recently completed phase II trials have consistently shown high survival, in spite of the relatively low incidence of major objective responses. | Trabectedin | tumor protein p53 | Homo sapiens |