PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 16533604-3 2006 ET-743, a DNA minor groove binder, which blocks cell cycle progression in G2/M phase through a p53-independent apoptotic process, represents the most promising among novel compounds in STS, since recently completed phase II trials have consistently shown high survival, in spite of the relatively low incidence of major objective responses. Trabectedin 0-6 tumor protein p53 Homo sapiens 95-98