Title : Inhibition of the insulin receptor tyrosine kinase by sphingosine.

Pub. Date : 1991 Aug 6

PMID : 1651108

1 Functional Relationships(s)
Compound Name
Protein Name
1 This lysosphingolipid has been shown previously to inhibit the Ca2+/lipid-dependent protein kinase C. Here we show that insulin-dependent autophosphorylation of partially purified insulin receptor is half-maximally inhibited by 145 microM sphingosine (9 mol %) in Triton X-100 micelles. Octoxynol insulin receptor Homo sapiens